Sr. HR Generalist

About Forge

At Forge Biologics, we believe in turning bold ideas into life-changing realities. Our mission is simple yet powerful: to enable access to life-changing gene therapies and help bring them from idea into reality. We partner with scientists, physicians, biotech and pharma innovators, and patient communities — all united by one goal: improving lives. If you’re driven by purpose and excited to make a tangible impact, this is where your journey begins.

Our team works out of The Hearth, a state-of-the-art, 200,000-square-foot cGMP facility in Columbus, Ohio. Here, you won’t just watch innovation happen — you’ll be part of it. Whether you’re scaling AAV manufacturing, collaborating on cutting-edge therapies, or supporting complex technical projects, you’ll play a key role in bringing hope to patients with genetic diseases.

About The Role

We are currently seeking a Sr. HR Generalist to join the Forge Biologics team. This is an exciting opportunity to join a growing company and be part of a team that will be instrumental to the growth of the organization. The Sr. HR Generalist performs a variety of complex human resources duties partnering closely with senior HR management and various managers across Forge Biologics in supporting HR processes and department-specific strategies. This position carries out responsibilities in the following functional areas: employee relations, training, performance management, onboarding, policy implementation, and employment law compliance. The Sr. HR Generalist is an essential part of the Human Resources team and will report to the Associate Director, Human Resources. This position will be based in Columbus, Ohio and allows for a hybrid work schedule.

What You'll Do

• Provides HR consultation and support to department managers and employees for assigned business units.


• Build and maintain positive coaching relationships with managers and leaders and provide guidance and support in addressing employee development and disciplinary matters.


• Conducts prompt, thorough, and neutral workplace investigations.


• Analyze trends and metrics to develop solutions, programs, and policies.


• Maintains proper documentation, partners with leadership on outcome, and ensures timely resolution and follow-up on employee relations issues.


• Performs routine tasks required to administer and execute human resource programs including but not limited to; disciplinary matters; disputes and investigations; performance and talent management; recognition, engagement; and development.


• Regularly review and update company policies and employee handbook to reflect regulatory changes and company practices.


• Partner with HR leadership to evaluate the need for policy changes and lead the creation of new policies when identified.


• Participate in HR projects that enhance employee experience, organizational effectiveness, and HR process improvement.


• Updates HRIS with new and changing information; ensures accuracy and integrity of information.


• Assist in providing coverage for the HR Operations on a temporary basis.


• Will temporarily assume responsibilities in the areas of benefits including open enrollment, leave of absence, and ADA.


• Maintain up-to-date knowledge of federal and state employment law and compliance requirements.

What You'll Bring

• 5+ years’ experience in Human Resources, with a focus on employee relations and performance management.


• Strong knowledge of HR policies and procedures.


• Software skills, including a high level of knowledge of PowerPoint, Word, Excel, and familiarity with an HRIS. Experience with ADP Workforce Now and Lattice a plus.


• Strong knowledge of Employment Laws (EEO, ADA, AA, FMLA, etc.).


• Must have a high level of interpersonal skills to handle sensitive and confidential situations.


• Demonstrated professionalism, reliability, flexibility, attention to detail, and an ability to maintain strict privacy of confidential data and information.


• Comfortable navigating changing priorities and balancing multiple tasks while remaining flexible and solution-focused.


• Collaborative team player who thrives in a dynamic, cross-functional environment.

Preferred Skills

• HR certification (SHRM, HRCI, or PHR).


• Experience with benefits administration.


• Prior experience in a startup or high-growth organization.

Work Environment and Physical Demands

This position works in a typical office environment where the physical work demands will vary depending on the specific tasks and duties required of the job. This is largely a sedentary role; persons holding office positions are generally subject to environmental conditions having the lighting, temperature, and noise of an open floor-plan office environment. Regularly operate a computer and other office equipment. Regularly communicate with others in person, over the phone, and electronically. Must be able to move and/or carry objects weighing up to 10 lbs.

This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee. Duties, responsibilities and activities may change or new ones may be assigned.

Forge Biologics is an equal opportunity employer dedicated to building an inclusive and diverse workforce.  Forge Biologics, provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

Forge Your Future with Us

What sets Forge apart is our culture of H.O.P.E. We are hardworking , showing up each day with determination and grit. We are open , creating a space where ideas flow freely and every voice is valued. We are purpose-driven , with every task directly tied to changing lives. And we are engaged , energized by the challenges we face and the milestones we achieve together.

At Forge, your growth matters. We’re committed to helping you expand your skills, take on new challenges, and develop your career through mentorship, hands-on learning, and opportunities for advancement. Our people are our greatest investment, and we’re proud to see team members grow with us.

If you’re ready to use your talent to help deliver hope to patients around the world, join us — and be part of something bigger than yourself.

We’ve Got You Covered

We take the health and happiness of our employees seriously and are consistently evaluating new ways to make our benefits truly Un FORGE ttable.

• Health, Dental, and Vision insurance that starts on your first day at Forge, with 90% of premiums covered for team members as well as dependents


• Competitive PTO (plus 14 paid company holidays)


• Annual bonus for all full-time employees


• 401(K) company match


• Fully-stocked kitchen with free food/drinks


• Onsite gym


• 12 weeks of paid parental leave - additional discount programs include childcare support & dependent care


• Employee Assistance Program


• Wellness benefits (financial planning services, mental health counseling, employer paid disability)


• Professional & Personal development resources