Principal Research Scientist I, In vitro Bioassay Lead

AbbVie
Madison, OH

Lead a team of scientists in the development and implementation of in vitro assays to support the progression of peptide therapeutics including biophysical biochemical and cellular assays.  Direct research and/or project activities and professional development of a group of scientists within the individuals area of expertise by effectively mentoring guiding and/or supervising scientific personnel.  Independently conceive execute and communicate novel multi-disciplinary research or development strategies that achieve project and area goals. Serve as a lead scientist on his/her own project and contribute scientific insights into multiple other projects.

Responsibilities

Lead a team of scientists in the design development and validation in vitro assays required to support ongoing peptide therapeutics programs.

Plan implement and oversee effective in vitro screening funnels required to advance therapeutic discovery projects.

Lead bioassay scientist in the scale up and automation of biochemical and cellular assays.

Effectively function as a principal investigator generating original technical ideas and research or development strategies.

Demonstrate creative out of the box thinking to solve difficult problems and champion new technologies to achieve project goals.

Independently responsible for project science within his/her area of expertise on one or more project teams.

Primary author of publications presentations regulatory documents and/or primary inventor of patents.

Mentor/supervise a team of one or more cross-functional scientists and evaluate the performance of those individuals; is accountable for the effective performance of the team/individuals.

Qualifications :

Qualifications

BS or equivalent education and extensive typically 14 years of experience; MS or equivalent education with typically 12 years of experience; PhD with typically 6 years of experience in biochemistry biology chemistry or related field.

Experience with the implementation and optimization of biophysical biochemical and/or cellular assays:

Experience with current binding and potency assay approaches such as ELISA TR-FRET and/or other assay platforms

Experience with current cell-based assay methodologies such as cytotoxicity assays reporter gene assays proliferation assays effector function assays etc.

High-throughput assay development and/or experience with automation platforms is ideal.

Proven track record of collaboration with a cross-functional team of scientists to advance therapeutic programs.

Experience developing new strategies approaches and/or initiatives to improve procedures and practices.

The ideal candidate will be hard-working self-motivated detail-oriented highly organized and able to adapt quickly to changes.

Must have strong communication skills including verbal written and scientific data presentation including the ability to independently author technical reports and presentations

Must be forward-thinking and able to contribute to scientific/technical discussions

This position is an on-site role in a lab-based function.  To be successful candidates must enjoy and thrive in an on-site highly collaborative lab environment with daily face-to-face cross-functional interactions between scientists.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.

  • We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.

  • This job is eligible to participate in our short-term incentive programs. 

  • This job is eligible to participate in our long-term incentive programs

Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:

No

Employment Type :

Full-time

Posted 2025-11-26

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