Intern Myeloid Diseases

A global biopharmaceutical company on a mission to Solve On, Incyte follows science to find solutions for patients with unmet medical needs. Through the discovery, development, and commercialization of proprietary therapeutics, Incyte has established a portfolio of first-in-class medicines for patients and a strong pipeline of products in Hematology, Oncology and Inflammation & Autoimmunity.

Headquartered in Wilmington, Delaware, Incyte has operations in North America, Europe, and Asia.

This 11-week summer internship is designed for senior undergraduate, Master’s, or PhD students seeking exposure to a professional, corporate environment. The internship is project-based, with each intern assigned one clearly defined project aligned to the hosting department’s priorities.

The role emphasizes learning, skill development, and practical application of academic knowledge while contributing to meaningful work.

Internship Overview:

Myeloproliferative neoplasms (MPNs) are a group of blood cancers that arise from genetic mutations in hematopoietic stem cells in the bone marrow. These mutations drive excessive production of mature blood cells and, in some patients, can lead to transformation into acute myeloid leukemia (AML), a highly aggressive disease with poor prognosis.

Current frontline therapies, such as JAK/STAT inhibitors, can help manage symptoms but do not eliminate the underlying disease. As a result, there is a critical need for next-generation, disease-modifying therapies that selectively target malignant cells while sparing healthy blood cells.

At Incyte, our research focus is to develop innovative therapeutic strategies that precisely target neoplastic MPN cells and improve outcomes for patients.

This internship will focus on the development and execution of cell-based assays to evaluate next-generation large and small molecules that selectively inhibit the pathogenic JAK/STAT signaling. The intern will:

• Identify and work with cell lines carrying disease-relevant genetic mutations

• Optimize cell culture conditions to support medium- to high-throughput screening assays

• Evaluate both small- and large- molecules for biological activity

• Perform functional assays using hematopoietic cells from healthy donors and MPN patients to assess compound effects on normal versus disease-associated blood cell differentiation

These studies will employ advanced technologies including flow cytometry and mass cytometry (CyTOF), providing hands-on exposure to cutting-edge tools widely used in biomedical research and drug discovery.

Learning Opportunities

The intern will gain practical experience in disease-relevant biological models and modern laboratory techniques, contributing directly to the development of novel therapeutic approaches for patients with unmet medical needs.

Skills and Techniques You Will Learn

Cell-based assays

• Mammalian cell culture (cell lines and primary cells)

• Cell viability and proliferation assays

• Cell cycle analysis

Flow cytometry and data interpretation

Molecular biology techniques

• qRT-PCR

• Western blotting

• Mass Cytometry

Data analysis and visualization tools

• GraphPad Prism

• FlowJo

• Cytolytics

Please note program duration: June 1 – August 14, 2026. 

Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.

Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.

We Respect Your Privacy

Learn more at:

The Incyte hiring organization processes your personal data to manage your job application in order to enter into an employment relationship with you if you are the successful candidate.
During the process, you may be asked to respond to questions that will screen out your application if you do not meet certain objective criteria required by the job. You can learn more about this process here .

You may have the right to access, delete, restrict, edit, move, or object to the use of your personal data. You may also have a right to report concerns to the authority responsible for data privacy in the country where the position is based or where you live or work. 

You can learn more about Incyte’s data protection practices here . By accessing this link you can learn about the types of personal data we collect, how we use it, whether collection and processing is optional, sources of the personal data we process, how it is shared, where it is stored or transferred to, how long we keep it, and contact information for Incyte, Incyte’s data protection officer, and your supervisory authority (if applicable).

Please contact [email protected] if you have any questions or concerns or would like to exercise your rights.